Reproductive Biology and Endocrinology

Saveria Aquila, Carmela Guido, Emilia Middea, +4

SpermatogenesisFertilityComparative EndocrinologyReproductive HealthGynecology +19

Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with “Warburg-like” cancer metabolism and L-lactate production

Carmela Guido, Diana Whitaker‐Menezes, Claudia Capparelli, +9

Cell Cycle

MitophagyMitochondrial DysfunctionConnecting Tgf-βCell ProliferationL-lactate Production +22

Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production

Claudia Capparelli, Carmela Guido, Diana Whitaker‐Menezes, +12

Cell Cycle

MitophagyKetone ProductionMitochondrial DysfunctionCancer-associated FibroblastsMetabolic Remodeling +17

CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth

Claudia Capparelli, Diana Whitaker‐Menezes, Carmela Guido, +8

Cell Cycle

Cancer-associated FibroblastsMetabolic RemodelingCancer BiologyTumor BiologyCell Autophagy +17

Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth

Renee M. Balliet, Claudia Capparelli, Carmela Guido, +9

Cell Cycle

Breast OncologyMitochondrial DysfunctionMitochondrial BiologyMetabolic RemodelingCancer Biology +15

Mitochondrial Fission Induces Glycolytic Reprogramming in Cancer-Associated Myofibroblasts, Driving Stromal Lactate Production, and Early Tumor Growth

Carmela Guido, Diana Whitaker‐Menezes, Zhao Lin, +9

Oncotarget

Human male gamete endocrinology: 1alpha, 25-dihydroxyvitamin D3 (1,25(OH)2D3) regulates different aspects of human sperm biology and metabolism

Saveria Aquila, Carmela Guido, Emilia Middea, +3

Reproductive Biology and Endocrinology

Human sperm anatomy: ultrastructural localization of 1α,25‐dihydroxyvitamin D₃ receptor and its possible role in the human male gamete

Saveria Aquila, Carmela Guido, Ida Perrotta, +3

Journal of Anatomy

Human Sperm Anatomy: Ultrastructural Localization of the Cannabinoid1 Receptor and a Potential Role of Anandamide in Sperm Survival and Acrosome Reaction

Saveria Aquila, Carmela Guido, Antonietta Santoro, +4

The Anatomical Record

SpermatogenesisHuman SpermSemen AnalysisReproductive BiologyCannabinoid Pharmacology +17

Estrogen receptor beta (ERβ) produces autophagy and necroptosis in human seminoma cell line through the binding of the Sp1 on the phosphatase and tensin homolog deleted from chromosome 10 (PTEN) promoter gene

Carmela Guido, Salvatore Panza, Marta Santoro, +11

Cell Cycle

Pten PromoterApoptosisImmunologyCell DeathNm Estradiol +22