Claudia Capparelli

Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with “Warburg-like” cancer metabolism and L-lactate production

Carmela Guido, Diana Whitaker‐Menezes, Claudia Capparelli et al. · Cell Cycle · 2012 · 303 citations · Full text

Mitophagy, Mitochondrial Dysfunction, Connecting Tgf-β +24

Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production

Claudia Capparelli, Carmela Guido, Diana Whitaker‐Menezes et al. · Cell Cycle · 2012 · 226 citations

Mitophagy, Ketone Production, Mitochondrial Dysfunction +19

CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angiogenesis

Claudia Capparelli, Barbara Chiavarina, Diana Whitaker‐Menezes et al. · Cell Cycle · 2012 · 222 citations · Full text

CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth

Claudia Capparelli, Diana Whitaker‐Menezes, Carmela Guido et al. · Cell Cycle · 2012 · 135 citations · Full text

Cancer-associated Fibroblasts, Metabolic Remodeling, Cancer Biology +19

Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth

Renee M. Balliet, Claudia Capparelli, Carmela Guido et al. · Cell Cycle · 2011 · 130 citations · Full text

Breast Oncology, Mitochondrial Dysfunction, Mitochondrial Biology +17