Ana Negri

PM01183, a new DNA minor groove covalent binder with potent <i>in vitro</i> and <i>in vivo</i> anti‐tumour activity

JFM Leal, Marta Martínez, Verónica García-Hernández et al. · British Journal of Pharmacology · 2010 · 149 citations · Full text

Predicting Binding Affinities for GPCR Ligands Using Free-Energy Perturbation

Eelke B. Lenselink, Julien Louvel, Anna F. Forti et al. · ACS Omega · 2016 · 145 citations · Full text

Identification of a μ-δ opioid receptor heteromer-biased agonist with antinociceptive activity

Ivone Gomes, Wakako Fujita, Achla Gupta et al. · Proceedings of the National Academy of Sciences · 2013 · 132 citations · Full text

Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening

Jieqing Zhu, Jianghai Zhu, Ana Negri et al. · Blood · 2010 · 110 citations · Full text

Ligand-Induced Modulation of the Free-Energy Landscape of G Protein-Coupled Receptors Explored by Adaptive Biasing Techniques

Davide Provasi, Marta Camacho Artacho, Ana Negri et al. · PLoS Computational Biology · 2011 · 95 citations · Full text

Engineering, Molecular Dynamics, Molecular Pharmacology +20