Ian M. Eggleston

Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines.

Christine Bonnesen, Ian M. Eggleston, John D. Hayes · PubMed · 2001 · 463 citations

Dna Damage, Chemoprevention Strategy, Apoptosis +18

Structural insights into the mechanism and inhibition of eukaryotic O‐GlcNAc hydrolysis

Francesco Rao, Helge C. Dorfmueller, Fabrizio Villa et al. · The EMBO Journal · 2006 · 195 citations · Full text

Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents

Larry G. Higgins, Michael Kelleher, Ian M. Eggleston et al. · Toxicology and Applied Pharmacology · 2009 · 172 citations

Inflammation, Cytotoxic Effects, Reductive Stress +12

Structure-Based Exploration of Cyclic Dipeptide Chitinase Inhibitors

Douglas R. Houston, Bjørnar Synstad, Vincent G. H. Eijsink et al. · Journal of Medicinal Chemistry · 2004 · 154 citations

Biochemistry, Natural Sciences, Medicine +12

A convenient synthesis of cyclic peptides as regioselectively addressable functionalized templates (RAFT)

Pascal Dumy, Ian M. Eggleston, Stefano E. Cervigni et al. · Tetrahedron Letters · 1995 · 116 citations

Engineering, Biochemistry, Peptide Engineering +8