Diffusion of docosahexaenoic and eicosapentaenoic acids through the blood–brain barrier: An in situ cerebral perfusion study

Mélissa Ouellet, Vincent Émond, Chuck T. Chen, +6

Neurochemistry International

Blood–brain BarrierEicosapentaenoic AcidsNeuroprotectionNeurologyNeuroscience +3

Rapid β-oxidation of eicosapentaenoic acid in mouse brain: An in situ study

Chuck T. Chen, Zhen Liu, Mélissa Ouellet, +2

Prostaglandins Leukotrienes and Essential Fatty Acids

Rapid β-OxidationBiochemistrySitu StudyLipid PeroxidationMouse Brain +5

Plasma non-esterified docosahexaenoic acid is the major pool supplying the brain

Chuck T. Chen, Alex P. Kitson, Kathryn E. Hopperton, +7

Scientific Reports

The low levels of eicosapentaenoic acid in rat brain phospholipids are maintained via multiple redundant mechanisms

Chuck T. Chen, Anthony F. Domenichiello, Marc‐Olivier Trépanier, +3

Journal of Lipid Research

The low density lipoprotein receptor is not necessary for maintaining mouse brain polyunsaturated fatty acid concentrations

Chuck T. Chen, David W.L., John H. Kim, +2

Journal of Lipid Research

Whole body synthesis rates of DHA from α-linolenic acid are greater than brain DHA accretion and uptake rates in adult rats

Anthony F. Domenichiello, Chuck T. Chen, Marc‐Olivier Trépanier, +2

Journal of Lipid Research

Effect of dietary docosahexaenoic acid (DHA) in phospholipids or triglycerides on brain DHA uptake and accretion

Alex P. Kitson, Adam H. Metherel, Chuck T. Chen, +4

The Journal of Nutritional Biochemistry

Wnt signaling activates MFSD2A to suppress vascular endothelial transcytosis and maintain blood-retinal barrier

Zhongxiao Wang, Chi‐Hsiu Liu, Shuo Huang, +9

Science Advances

Rapid de-esterification and loss of eicosapentaenoic acid from rat brain phospholipids: an intracerebroventricular study

Chuck T. Chen, Zhen Liu, Richard P. Bazinet

Journal of Neurochemistry

Lipid AnalysisIntact EpaFatty AcidsRapid De-esterificationEicosapentaenoic Acid +17

The effect of linoleic acid on the whole body synthesis rates of polyunsaturated fatty acids from α-linolenic acid and linoleic acid in free-living rats

Anthony F. Domenichiello, Alex P. Kitson, Chuck T. Chen, +3

The Journal of Nutritional Biochemistry

Experimental NutritionLinoleic AcidMolecular NutritionPublic HealthMetabolic Signaling +14