Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach

Anne K. Krug, Raivo Kolde, John Antonydas Gaspar, +35

Archives of Toxicology

GeneticsTranscriptomics ApproachCerebral OrganoidTest SystemEpigenetics +20

Evaluation of Developmental Toxicants and Signaling Pathways in a Functional Test Based on the Migration of Human Neural Crest Cells

Bastian Zimmer, Gabsang Lee, Nina V. Balmer, +4

Environmental Health Perspectives

Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue

Patrício Godoy, Agata Widera, Wolfgang Schmidt‐Heck, +29

Archives of Toxicology

Identification of Thalidomide-Specific Transcriptomics and Proteomics Signatures during Differentiation of Human Embryonic Stem Cells

Kesavan Meganathan, Smita Jagtap, Vilas Wagh, +8

PLoS ONE

GeneticsTranscriptomics TechnologyStem Cell BiologyCell SpecializationProteomics Signatures +19

From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects

Nina V. Balmer, Stefanie Klima, Eugen Rempel, +11

Archives of Toxicology

Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development

Kesavan Meganathan, Emily M.A. Lewis, Paul Gontarz, +6

Proceedings of the National Academy of Sciences

Development of a Neural Teratogenicity Test Based on Human Embryonic Stem Cells: Response to Retinoic Acid Exposure

Silvia Colleoni, Cesare Galli, John Antony Gaspar, +5

Toxicological Sciences

GeneticsAdult Stem CellRetinoic AcidEmbryologyStem Cells +15

Human Skin-Derived Stem Cells as a Novel Cell Source for In Vitro Hepatotoxicity Screening of Pharmaceuticals

Robim M. Rodrigues, Joery De Kock, Steven Branson, +9

Stem Cells and Development

Tissue EngineeringAdult Stem CellImmunologyDermatologyStem Cell Transplantation +20

Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests

Vaibhav Shinde, Lisa Hoelting, Sureshkumar Perumal Srinivasan, +19

Archives of Toxicology

Mesoderm-Derived Stem Cells: The Link Between the Transcriptome and Their Differentiation Potential

Joery De Kock, Mehdi Najar, Jennifer Bolleyn, +13

Stem Cells and Development

Tissue EngineeringEngineeringAdult Stem CellHuman WhartonCell Differentiation +19