Carlotta Costa

Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

Aaron N. Hata, Matthew J. Niederst, Hannah L. Archibald et al. · Nature Medicine · 2016 · 968 citations · Full text

Tumor Biology, Developmental Biology, Distinct Evolutionary Paths +7

RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer

Matthew J. Niederst, Lecia V. Sequist, John T. Poirier et al. · Nature Communications · 2015 · 619 citations · Full text

CDK 4/6 Inhibitors Sensitize PIK3CA Mutant Breast Cancer to PI3K Inhibitors

Sadhna Vora, Dejan Juric, Nayoon Kim et al. · Cancer Cell · 2014 · 428 citations · Full text

Pi3k Inhibitors, Breast Oncology, Medicine +10

MEK Inhibition Leads to PI3K/AKT Activation by Relieving a Negative Feedback on ERBB Receptors

Alexa B. Turke, Youngchul Song, Carlotta Costa et al. · Cancer Research · 2012 · 355 citations · Full text

Phosphoinositide 3-Kinase p110β Activity: Key Role in Metabolism and Mammary Gland Cancer but Not Development

Elisa Ciraolo, Manuela Iezzi, Romina Marone et al. · Science Signaling · 2008 · 262 citations · Full text

Breast Oncology, Key Role, Metabolic Remodeling +24