Roberta Costi

Geometrically and Conformationally Restrained Cinnamoyl Compounds as Inhibitors of HIV-1 Integrase:  Synthesis, Biological Evaluation, and Molecular Modeling

Marino Artico, Roberto Di Santo, Roberta Costi et al. · Journal of Medicinal Chemistry · 1998 · 162 citations · Full text

Combinatorial Chemistry, Hiv-1 Integrase, Enzyme Assays +17

Antimycobacterial pyrroles: synthesis, anti-Mycobacterium tuberculosis activity and QSAR studies

Rino Ragno, Garland R. Marshall, Roberto Di Santo et al. · Bioorganic & Medicinal Chemistry · 2000 · 132 citations

6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro

Enzo Tramontano, Francesca Esposito, Roberta Badas et al. · Antiviral Research · 2005 · 117 citations

Medicinal Chemistry, Viral Replication, Hiv-1 Viral Replication +13

Antifungal Agents. 11.<i>N</i>-Substituted Derivatives of 1-[(Aryl)(4-aryl-1<i>H</i>-pyrrol-3-yl)methyl]-1<i>H</i>-imidazole:  Synthesis, Anti-<i>Candida</i>Activity, and QSAR Studies

Roberto Di Santo, Andrea Tafi, Roberta Costi et al. · Journal of Medicinal Chemistry · 2005 · 116 citations

Novel Bifunctional Quinolonyl Diketo Acid Derivatives as HIV-1 Integrase Inhibitors:  Design, Synthesis, Biological Activities, and Mechanism of Action

Roberto Di Santo, Roberta Costi, Alessandra Roux et al. · Journal of Medicinal Chemistry · 2006 · 85 citations · Full text

Hiv-1 Integrase, Encoded Integrase Protein, Biological Activities +16