Francesca Esposito

Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen

Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen et al. · ACS Pharmacology & Translational Science · 2021 · 154 citations · Full text

6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro

Enzo Tramontano, Francesca Esposito, Roberta Badas et al. · Antiviral Research · 2005 · 117 citations

Medicinal Chemistry, Viral Replication, Hiv-1 Viral Replication +13

Single Delivery of an Adeno-Associated Viral Construct to Transfer the <i>CASQ2</i> Gene to Knock-In Mice Affected by Catecholaminergic Polymorphic Ventricular Tachycardia Is Able to Cure the Disease From Birth to Advanced Age

Marco Denegri, Rossana Bongianino, Francesco Lodola et al. · Circulation · 2014 · 113 citations · Full text

HIV-1 Reverse Transcriptase Still Remains a New Drug Target: Structure, Function, Classical Inhibitors, and New Inhibitors with Innovative Mechanisms of Actions

Francesca Esposito, Angela Corona, Enzo Tramontano · Molecular Biology International · 2012 · 102 citations · Full text

Nnrtis Bind, Immunology, Molecular Biology +19

Structural and Biochemical Analysis of the Dual Inhibition of MG-132 against SARS-CoV-2 Main Protease (Mpro/3CLpro) and Human Cathepsin-L

Elisa Costanzi, Maria Kuzikov, Francesca Esposito et al. · International Journal of Molecular Sciences · 2021 · 84 citations · Full text

Protein Assembly, Immunology, Antiviral Drug +19