Joel O. Melby

YcaO domains use ATP to activate amide backbones during peptide cyclodehydrations

Kyle L. Dunbar, Joel O. Melby, Douglas A. Mitchell · Nature Chemical Biology · 2012 · 131 citations · Full text

Protein Chemistry, Biochemistry, Natural Sciences +7

Structure, Bioactivity, and Resistance Mechanism of Streptomonomicin, an Unusual Lasso Peptide from an Understudied Halophilic Actinomycete

Mikhail Metelev, Jonathan I. Tietz, Joel O. Melby et al. · Chemistry & Biology · 2015 · 92 citations · Full text

Biosynthesis, Unusual Lasso Peptide, Biochemistry +9

Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS

Qi Zhang, Manuel A. Ortega, Yanxiang Shi et al. · Proceedings of the National Academy of Sciences · 2014 · 67 citations · Full text

Nucleophilic 1,4-Additions for Natural Product Discovery

Courtney Cox, Jonathan I. Tietz, Karol Sokolowski et al. · ACS Chemical Biology · 2014 · 65 citations · Full text

Medicinal Chemistry, Available Thiol, Engineering +15

Orchestration of Enzymatic Processing by Thiazole/Oxazole-Modified Microcin Dehydrogenases

Joel O. Melby, Xiangpo Li, Douglas A. Mitchell · Biochemistry · 2013 · 64 citations · Full text

Bioorganic Chemistry, Engineering, Heterocycle Biosynthesis +17