Concepedia

Manuel A. Ortega

MA

10

Publications

805

Citations

10

H-Index

2010

Active since

Affiliations

Howard Hughes Medical Institute(Current)

University of Illinois Urbana-Champaign

Beam Therapeutics (United States)

Manuel A. Ortega is an author at Howard Hughes Medical Institute specializing in biochemistry, biosynthesis, and medicine.

Top concepts

Publications per year

2010–2023

10

Publications

10

Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB

Manuel A. Ortega, Yue Hao, Qi Zhang et al. · Nature · 2014 · 317 citations · Full text

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Improved cytosine base editors generated from TadA variants

Dieter K. Lam, Patrícia R. Feliciano, Amena Arif et al. · Nature Biotechnology · 2023 · 129 citations · Full text

Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis

Manuel A. Ortega, D.P. Cogan, Subha Mukherjee et al. · ACS Chemical Biology · 2016 · 81 citations · Full text

Structure and tRNA Specificity of MibB, a Lantibiotic Dehydratase from Actinobacteria Involved in NAI-107 Biosynthesis

Manuel A. Ortega, Yue Hao, Mark C. Walker et al. · Cell chemical biology · 2016 · 80 citations · Full text

, , +7

Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS

Qi Zhang, Manuel A. Ortega, Yanxiang Shi et al. · Proceedings of the National Academy of Sciences · 2014 · 67 citations · Full text

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