Jonathan I. Tietz

A new genome-mining tool redefines the lasso peptide biosynthetic landscape

Jonathan I. Tietz, Christopher J. Schwalen, Parth Patel et al. · Nature Chemical Biology · 2017 · 499 citations · Full text

Bioinformatics, Translational Bioinformatics, New Genome-mining Tool +13

In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin

Graham A. Hudson, Zhengan Zhang, Jonathan I. Tietz et al. · Journal of the American Chemical Society · 2015 · 168 citations · Full text

Structure, Bioactivity, and Resistance Mechanism of Streptomonomicin, an Unusual Lasso Peptide from an Understudied Halophilic Actinomycete

Mikhail Metelev, Jonathan I. Tietz, Joel O. Melby et al. · Chemistry & Biology · 2015 · 92 citations · Full text

Biosynthesis, Unusual Lasso Peptide, Biochemistry +9

Biosynthetic Timing and Substrate Specificity for the Thiopeptide Thiomuracin

Zhengan Zhang, Graham A. Hudson, Nilkamal Mahanta et al. · Journal of the American Chemical Society · 2016 · 91 citations

Combinatorial Chemistry, Medicinal Chemistry, Biosynthesis +12

Nucleophilic 1,4-Additions for Natural Product Discovery

Courtney Cox, Jonathan I. Tietz, Karol Sokolowski et al. · ACS Chemical Biology · 2014 · 65 citations · Full text

Medicinal Chemistry, Available Thiol, Engineering +15