Derek A. Costello

Iron accumulation in microglia triggers a cascade of events that leads to altered metabolism and compromised function in APP/PS1 mice

Allison McIntosh, Virginia Mela, Conor Harty et al. · Brain Pathology · 2019 · 190 citations · Full text

Long Term Potentiation Is Impaired in Membrane Glycoprotein CD200-deficient Mice

Derek A. Costello, Anthony Lyons, Stephanie Denieffe et al. · Journal of Biological Chemistry · 2011 · 145 citations · Full text

Toll‐like receptor 3 activation modulates hippocampal network excitability, via glial production of interferon‐β

Derek A. Costello, Marina A. Lynch · Hippocampus · 2013 · 77 citations

Microbial Pathogens, Adaptive Immune System, Innate Immune System +27

Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli

James P. Barrett, Derek A. Costello, Joan B. O’Sullivan et al. · Journal of Neuroinflammation · 2015 · 75 citations · Full text

Brain Deletion of Insulin Receptor Substrate 2 Disrupts Hippocampal Synaptic Plasticity and Metaplasticity

Derek A. Costello, Marc Claret, Hind Al‐Qassab et al. · PLoS ONE · 2012 · 72 citations · Full text