Jennifer H. Johnson

Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity

Rakesh Kumar, Victoria B. Knick, Sharon K. Rudolph et al. · Molecular Cancer Therapeutics · 2007 · 517 citations

Medicine, Pharmacokinetics, Pharmacology +17

Discovery of 5-[[4-[(2,3-Dimethyl-2<i>H</i>-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor

Philip A. Harris, Amogh Boloor, Mui Cheung et al. · Journal of Medicinal Chemistry · 2008 · 345 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Inhibition of colony-stimulating-factor-1 signaling <i>in vivo</i> with the orally bioavailable cFMS kinase inhibitor GW2580

James G. Conway, Brad McDonald, Janet H. Parham et al. · Proceedings of the National Academy of Sciences · 2005 · 252 citations · Full text

Life Sciences, Pharmacology, Bone Metabolism +14

MicroRNA 132 Regulates Nutritional Stress-Induced Chemokine Production through Repression of SirT1

Jay C. Strum, Jennifer H. Johnson, James M. Ward et al. · Molecular Endocrinology · 2009 · 221 citations · Full text

Life Sciences, Immunology, Physiology +17

The Vascular Endothelial Growth Factor (VEGF) Receptor Flt-1 (VEGFR-1) Modulates Flk-1 (VEGFR-2) Signaling During Blood Vessel Formation

David M. Roberts, Joseph B. Kearney, Jennifer H. Johnson et al. · American Journal Of Pathology · 2004 · 191 citations · Full text

Life Sciences, Developmental Biology, Physiology +13