Yiguo Hu

Pan-cancer single-cell analysis reveals the heterogeneity and plasticity of cancer-associated fibroblasts in the tumor microenvironment

Han Luo, Xuyang Xia, Li‐Bin Huang et al. · Nature Communications · 2022 · 559 citations · Full text

Medicine, Cancer Biology, Oncology +13

SARS-CoV-2 M ^pro inhibitors with antiviral activity in a transgenic mouse model

Jingxin Qiao, Yueshan Li, Rui Zeng et al. · Science · 2021 · 450 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma

Naoya Mimura, Mariateresa Fulciniti, Güllü Görgün et al. · Blood · 2012 · 435 citations · Full text

Life Sciences, Molecular Biology, Molecular Medicine +9

Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia

Yiguo Hu, Yuhua Liu, Shawn D. Pelletier et al. · Nature Genetics · 2004 · 404 citations

Medicine, Cancer Biology, Oncology +9

A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance

Ze Tian, Pádraig D’Arcy, Xin Wang et al. · Blood · 2013 · 312 citations · Full text

Medicine, Molecular Biology, Oncology +17