Christopher Shenton

Aβ42 Mutants with Different Aggregation Profiles Induce Distinct Pathologies in Drosophila

Koichi Iijima, Hsueh‐Cheng Chiang, Stephen Hearn et al. · PLoS ONE · 2008 · 167 citations · Full text

Genetics, Aβ42 Mutants, Molecular Genetics +16

Mitochondrial Mislocalization Underlies Aβ42-Induced Neuronal Dysfunction in a Drosophila Model of Alzheimer's Disease

Kanae Iijima‐Ando, Stephen Hearn, Christopher Shenton et al. · PLoS ONE · 2009 · 120 citations · Full text

Genetics, Neurochemical Biomarkers, Synaptic Signaling +16

Overexpression of Neprilysin Reduces Alzheimer Amyloid-β42 (Aβ42)-induced Neuron Loss and Intraneuronal Aβ42 Deposits but Causes a Reduction in cAMP-responsive Element-binding Protein-mediated Transcription, Age-dependent Axon Pathology, and Premature Death in Drosophila

Kanae Iijima‐Ando, Stephen Hearn, Linda Granger et al. · Journal of Biological Chemistry · 2008 · 73 citations · Full text

A DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration

Kanae Iijima‐Ando, Lijuan Zhao, Anthony Gatt et al. · Human Molecular Genetics · 2010 · 71 citations · Full text

Genome Instability, Neurodegenerative Diseases, Mitophagy +15

Regulation of Energy Stores and Feeding by Neuronal and Peripheral CREB Activity in Drosophila

Koichi Iijima, Lijuan Zhao, Christopher Shenton et al. · PLoS ONE · 2009 · 64 citations · Full text

Food Intake, Creb Activity, Peripheral Creb Activity +18