Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

Aaron N. Hata, Matthew J. Niederst, Hannah L. Archibald, +27

Nature Medicine

Tumor BiologyDevelopmental BiologyDistinct Evolutionary PathsMedicineTumor Cells +5

Intrinsic Disorder Is a Common Feature of Hub Proteins from Four Eukaryotic Interactomes

Chad Haynes, Christopher J. Oldfield, Fei Ji, +6

PLoS Computational Biology

Predicted Structural DisorderProtein AssemblyGeneticsConsensus Prediction MethodMolecular Biology +21

YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation

Chuanzhao Zhang, Shanzhou� Huang, Hongkai Zhuang, +7

Oncogene

Tumor BiologyTranscriptional RegulationM6a Rna MethylationMedicineOct4 Expression +10

Polycomb Repressive Complex 1 Generates Discrete Compacted Domains that Change during Differentiation

Sharmistha Kundu, Fei Ji, Hongjae Sunwoo, +5

Molecular Cell

Pattern FormationDiscrete Differential Geometry

Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

Vanessa Frodermann, David Rohde, Gabriel Courties, +29

Nature Medicine

Physical ActivityAerobic ExerciseImmunologyExercise MedicineHematopoietic Progenitor Cells +15

Genomic Analysis Defines a Cancer-Specific Gene Expression Signature for Human Squamous Cell Carcinoma and Distinguishes Malignant Hyperproliferation from Benign Hyperplasia

Asifa Haider, Sara Peters, Helen G. Kaporis, +6

Journal of Investigative Dermatology

Distinguishes Malignant HyperproliferationGenomic AnalysisPathologyCancer GenomicsBenign Hyperplasia +7

Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling

Justin Brumbaugh, Bruno Di Stefano, Xiuye Wang, +13

Cell

ChromatinTranscriptional RegulationChromatin StructureChromatin RemodelingCell Regulation +11

The first case of ischemia-free organ transplantation in humans: A proof of concept

Xiaoshun He, Zhiyong Guo, Qiang Zhao, +23

American Journal of Transplantation

The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis

Bruno Di Stefano, En‐Ching Luo, Chuck Haggerty, +19

Cell stem cell

P-body HomeostasisMolecular RegulationNatural SciencesRna BiologyMolecular Biology +7

Longitudinal MRI-based fusion novel model predicts pathological complete response in breast cancer treated with neoadjuvant chemotherapy: a multicenter, retrospective study

Yühong Huang, Teng Zhu, Xiaoling Zhang, +10

EClinicalMedicine