Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling

Michael P. Seiler, Rebecca Mathew, Megan K. Liszewski, +5

Nature Immunology

Transcriptional RegulationSignal TransductionSignaling PathwayLymphocyte DevelopmentTranscription Factors Egr1 +6

PLZF induces an intravascular surveillance program mediated by long-lived LFA-1–ICAM-1 interactions

Seddon Y. Thomas, Seth Thomas Scanlon, Klaus Griewank, +6

The Journal of Experimental Medicine

Aristaless Controls Butterfly Wing Color Variation Used in Mimicry and Mate Choice

Erica L. Westerman, Nicholas W. VanKuren, Darli Massardo, +11

Current Biology

BiologyPattern FormationFitnessNatural SciencesAvian Locomotion +5

Identification of an allosteric binding site for RORγt inhibition

Marcel Scheepstra, S. Leysen, Geert C. van Almen, +19

Nature Communications

Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis

Chiaowen Joyce Hsiao, Po‐Yuan Tung, John Blischak, +5

Genome Research

Single-cell sequencing reveals lineage-specific dynamic genetic regulation of gene expression during human cardiomyocyte differentiation

Reem Elorbany, Joshua M Popp, Katherine Rhodes, +5

PLoS Genetics

EngineeringCardiac Progenitor CellsGene Expression ProfilingTrajectory AnalysisSingle Cell Sequencing +18

Inhibition of RORγT Skews TCRα Gene Rearrangement and Limits T Cell Repertoire Diversity

Yanxia Guo, Kenzie D. MacIsaac, Yi Chen, +23

Cell Reports

Egr2-dependent gene expression profiling and ChIP-Seq reveal novel biologic targets in T cell anergy

Yan Zheng, Yuanyuan Zha, Robbert M. Spaapen, +4

Molecular Immunology

T Cell AnergyImmunogeneticsAutoimmune DiseaseMedicineT-regulatory Cell +9

Divergence in alternative polyadenylation contributes to gene regulatory differences between humans and chimpanzees

Briana E. Mittleman, Sebastian Pott, Shane Warland, +3

eLife

GeneticsAlternative Polyadenylation ContributesGenomic MechanismGene CharacterizationMolecular Genetics +18

Human embryoid bodies as a novel system for genomic studies of functionally diverse cell types

Katherine Rhodes, Kenneth Barr, Joshua M Popp, +3

eLife