Concepedia

S. Leysen

SL

Statistics

Publications

22

Citations

876

H-Index

15

Active since

2010

Affiliations

Eindhoven University of Technology(Current)

University of Duisburg-Essen

UCB Pharma (United Kingdom)

Centre National de la Recherche Scientifique

S. Leysen is an author at Eindhoven University of Technology specializing in life sciences, ligand binding, and protein structure.

Publications per year

2010–2023

22

Publications

22

Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR

Loes M. Stevers, Chan Vinh Lam, S. Leysen et al. · Proceedings of the National Academy of Sciences · 2016 · 135 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Site-Directed Fragment-Based Screening for the Discovery of Protein–Protein Interaction Stabilizers

Eline Sijbesma, Kenneth K. Hallenbeck, S. Leysen et al. · Journal of the American Chemical Society · 2019 · 114 citations

Life Sciences, Biochemistry, Medicinal Chemistry +17

Identification of an allosteric binding site for RORγt inhibition

Marcel Scheepstra, S. Leysen, Geert C. van Almen et al. · Nature Communications · 2015 · 102 citations · Full text

Life Sciences, Immunology, Medicinal Chemistry +17

Stabilizer‐Guided Inhibition of Protein–Protein Interactions

L.‐G. Milroy, Maria Bartel, Morkos A. Henen et al. · Angewandte Chemie International Edition · 2015 · 66 citations

Life Sciences, Medicinal Chemistry, Pharmacology +15

Characterization of Coding/Noncoding Variants for SHROOM3 in Patients with CKD

Jeremy W. Prokop, Nan Cher Yeo, Christian Ottmann et al. · Journal of the American Society of Nephrology · 2018 · 60 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

1–5 of 22