The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, +26

Cell

BioinformaticsEngineeringInteractomicsComplex Biological SystemBiological Network +9

Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase

Virgínia Guarani, Gianluca Deflorian, Cláudio A. Franco, +15

Nature

Transcriptional RegulationSignal TransductionSignaling PathwayCell RegulationMolecular Pathway +10

Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization

Wen Yang, Koji Nagasawa, Christian Münch, +12

Cell

Reductive StressSignal TransductionMembrane DepolarizationMitochondrial FunctionMitochondrial Dynamic +6

QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology

Virgínia Guarani, Elizabeth M. McNeill, João A. Paulo, +5

eLife

Molecular BiologyMolecular GeneticsNovel Mitochondrial ProteinCellular PhysiologyProteomics +14

Biallelic Mutations in DNAJC12 Cause Hyperphenylalaninemia, Dystonia, and Intellectual Disability

Yair Anikster, Tobias B. Haack, Thierry Vilboux, +36

The American Journal of Human Genetics

Genome InstabilityBiallelic MutationsMendelian DisorderGenetic DisorderGenetics +6

Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1

Jes-Niels Boeckel, Virgínia Guarani, Masamichi Koyanagi, +7

Proceedings of the National Academy of Sciences

Endothelial CellsImmunologyAngiogenic SproutingSplicing VariantTranscriptional Regulation +15

TIMMDC1/C3orf1 Functions as a Membrane-Embedded Mitochondrial Complex I Assembly Factor through Association with the MCIA Complex

Virgínia Guarani, João A. Paulo, Bo Zhai, +3

Molecular and Cellular Biology

Molecular BiologyCytoskeletonCore SubunitsTimmdc1/c3orf1 FunctionsMitochondrial Biogenesis +19

Dissecting coronary angiogenesis: 3D co-culture of cardiomyocytes with endothelial or mesenchymal cells

Luciana Ribeiro Garzoni, Maria Isabel D. Rossi, Ana Paula D. N. de Barros, +9

Experimental Cell Research

Regenerative MedicineTissue EngineeringAngiogenesisEngineeringCoronary Angiogenesis +11

QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease

Virgínia Guarani, Claude Jardel, Dominique Chrétien, +18

eLife