Abdulkarim Najjar

Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment

Abdulkarim Najjar, Ans Punt, John F. Wambaugh et al. · Archives of Toxicology · 2022 · 37 citations · Full text

Cosmetics Europe evaluation of 6 in silico skin penetration models

Sebastien Grégoire, Ian Sorrell, Daniela Lange et al. · Computational Toxicology · 2021 · 33 citations · Full text

Dd Prediction, Adme Tf, Pharmacokinetic Modeling +14

Computer-aided design, synthesis and biological characterization of novel inhibitors for PKMYT1

Abdulkarim Najjar, Charlott Platzer, Anton Luft et al. · European Journal of Medicinal Chemistry · 2018 · 23 citations · Full text

Medicinal Chemistry, Drug Target, Bioorganic Chemistry +12

Discovery of novel substituted benzo-anellated 4-benzylamino pyrrolopyrimidines as dual EGFR and VEGFR2 inhibitors

Tim Fischer, Thomas Krüger, Abdulkarim Najjar et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 22 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +11

Development of a microphysiological skin-liver-thyroid Chip3 model and its application to evaluate the effects on thyroid hormones of topically applied cosmetic ingredients under consumer-relevant conditions

Thi‐Phuong Tao, Ilka Maschmeyer, Edward L. LeCluyse et al. · Frontiers in Pharmacology · 2023 · 18 citations · Full text