Christine Brotherton‐Pleiss

Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-Benzyl derivatives with broad potency against resistant mutant viruses

D Kertesz, Christine Brotherton‐Pleiss, Minmin Yang et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 71 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

Discovery and optimization of RO-85, a novel drug-like, potent, and selective P2X3 receptor antagonist

Christine Brotherton‐Pleiss, Michael P. Dillon, Anthony Ford et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 41 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

Discovery of a Potent (4<i>R</i>,5<i>S</i>)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling

Huifen Chen, Matthew Volgraf, Steven Do et al. · Journal of Medicinal Chemistry · 2018 · 39 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of Novel Azetidine Amides as Potent Small-Molecule STAT3 Inhibitors

Christine Brotherton‐Pleiss, Peibin Yue, Yinsong Zhu et al. · Journal of Medicinal Chemistry · 2020 · 36 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Novel Series of Dihydropyridinone P2X7 Receptor Antagonists

Francisco Lopez‐Tapia, Keith A. M. Walker, Christine Brotherton‐Pleiss et al. · Journal of Medicinal Chemistry · 2015 · 29 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14