Concepedia
Statistics
Publications
7
Citations
263
H-Index
Active since
2017
Affiliations
University of Toronto(Current)
Hospital for Sick Children
Université Laval
Central Drug Research Institute
Rockefeller University
Amit Laxmikant Deshmukh is an author at University of Toronto specializing in medicine, systems biology, and drug discovery.
Top concepts
MedicinePathologyPharmacologyDrug DiscoverySystems BiologyMedicinal ChemistryEngineeringBiochemistryNanomedicineGene Delivery
Publications per year
2017–2024
Cell-type-specific CAG repeat expansions and toxicity of mutant Huntingtin in human striatum and cerebellum
Matthew Baffuto, Laura Kus, Amit Laxmikant Deshmukh et al. · Nature Genetics · 2024 · 110 citations · Full text
Identification of human flap endonuclease 1 (FEN1) inhibitors using a machine learning based consensus virtual screening
Amit Laxmikant Deshmukh, Sharat Chandra, Deependra Kumar Singh et al. · Molecular BioSystems · 2017 · 35 citations
Drug Target, Engineering, Hit Identification +17
FAN1 exo- not endo-nuclease pausing on disease-associated slipped-DNA repeats: A mechanism of repeat instability
Amit Laxmikant Deshmukh, Marie‐Christine Caron, Mohiuddin Mohiuddin et al. · Cell Reports · 2021 · 33 citations · Full text
A Novel Benzocoumarin-Stilbene Hybrid as a DNA ligase I inhibitor with in vitro and in vivo anti-tumor activity in breast cancer models
Mohd Kamil Hussain, Deependra Kumar Singh, Akhilesh Singh et al. · Scientific Reports · 2017 · 26 citations · Full text
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic et al. · Cell · 2023 · 25 citations · Full text
Signal Transduction, Autoimmune Disease, Molecular Physiology +5
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