Sharat Chandra

Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice

Sangsu Bang, Christopher R. Donnelly, Xin Luo et al. · Nature Communications · 2021 · 87 citations · Full text

Discovery of pancreastatin inhibitor PSTi8 for the treatment of insulin resistance and diabetes: studies in rodent models of diabetes mellitus

Zakir Hossain, Guru R. Valicherla, Anand P. Gupta et al. · Scientific Reports · 2018 · 42 citations · Full text

Pancreastatin Inhibitor Psti8, Insulin Signaling, Metabolic Syndrome +16

Identification of human flap endonuclease 1 (FEN1) inhibitors using a machine learning based consensus virtual screening

Amit Laxmikant Deshmukh, Sharat Chandra, Deependra Kumar Singh et al. · Molecular BioSystems · 2017 · 35 citations

Drug Target, Engineering, Hit Identification +17

Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission

Michele Yeo, Yong Chen, Changyu Jiang et al. · Nature Communications · 2021 · 31 citations · Full text

Synthetic FXR Agonist GW4064 Is a Modulator of Multiple G Protein–Coupled Receptors

Nidhi Singh, Manisha Yadav, Abhishek Kumar Singh et al. · Molecular Endocrinology · 2014 · 29 citations · Full text

Molecular Regulation, Histamine Receptor Modulation, Molecular Pharmacology +18