Emma T. van der Westhuizen

Quantification of Ligand Bias for Clinically Relevant β2-Adrenergic Receptor Ligands: Implications for Drug Taxonomy

Emma T. van der Westhuizen, Billy Breton, Arthur Christopoulos et al. · Molecular Pharmacology · 2013 · 233 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist

Matthieu Masureel, Yaozhong Zou, Louis-Philippe Picard et al. · Nature Chemical Biology · 2018 · 203 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Impedance Responses Reveal β2-Adrenergic Receptor Signaling Pluridimensionality and Allow Classification of Ligands with Distinct Signaling Profiles

Wayne Stallaert, Jonas F. Dorn, Emma T. van der Westhuizen et al. · PLoS ONE · 2012 · 97 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

The Relaxin Family Peptide Receptor 3 Activates Extracellular Signal-Regulated Kinase 1/2 through a Protein Kinase C-Dependent Mechanism

Emma T. van der Westhuizen, Tim D. Werry, Patrick M. Sexton et al. · Molecular Pharmacology · 2007 · 92 citations

Life Sciences, Biochemistry, Molecular Biology +17

Purinergic Receptor Transactivation by the β2-Adrenergic Receptor Increases Intracellular Ca2+ in Nonexcitable Cells

Wayne Stallaert, Emma T. van der Westhuizen, Anne-Marie Schönegge et al. · Molecular Pharmacology · 2017 · 83 citations

Life Sciences, Cell Biology, Pharmacology +17