Patrick M. Sexton

Activation and allosteric modulation of a muscarinic acetylcholine receptor

Andrew C. Kruse, Aaron M. Ring, Aashish Manglik et al. · Nature · 2013 · 896 citations · Full text

Functional Selectivity, Medicine, Synaptic Transmission +6

Multiple Amylin Receptors Arise from Receptor Activity-Modifying Protein Interaction with the Calcitonin Receptor Gene Product

George Christopoulos, Katie J. Perry, Maria Morfis et al. · Molecular Pharmacology · 1999 · 478 citations

Signal Transduction, G Protein-coupled Receptor, Medicine +6

Phase-plate cryo-EM structure of a class B GPCR–G-protein complex

Yi-Lynn Liang, Maryam Khoshouei, Mazdak Radjainia et al. · Nature · 2017 · 474 citations · Full text

Protein X-ray Crystallography, Molecular Biology, Phase-plate Cryo-em Structure +2

Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization.

Geoffrey C. Nicholson, Jane M. Moseley, Patrick M. Sexton et al. · Journal of Clinical Investigation · 1986 · 457 citations · Full text

Engineering, Cytoskeleton, Cellular Physiology +19

Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs

Ron O. Dror, Hillary F. Green, Céline Valant et al. · Nature · 2013 · 420 citations

Molecular Pharmacology, Drug Target, Biochemistry +11