Claus Nerlov

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal

Eric M. Pietras, Cristina Mirantes-Barbeito, Sarah Fong et al. · Nature Cell Biology · 2016 · 677 citations

Inflammation, Developmental Biology, Bone Marrow Failure +13

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy

Alejandra Sanjuán-Pla, Iain C. Macaulay, Christina T. Jensen et al. · Nature · 2013 · 617 citations

Thrombopoiesis, Developmental Biology, Bone Marrow Failure +11

A CREB-C/EBPβ cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair

Daniela Ruffell, Foteini Mourkioti, Adriana Rosa Gambardella et al. · Proceedings of the National Academy of Sciences · 2009 · 610 citations · Full text

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction

Ann-Marie E Bröske, Lena Vockentanz, Shabnam Kharazi et al. · Nature Genetics · 2009 · 457 citations

Chromatin, Medicine, Genetics +10

Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block

Peggy Kirstetter, Kristina Anderson, Bo Porse et al. · Nature Immunology · 2006 · 438 citations

Canonical Wnt Pathway, Developmental Biology, Medicine +6