Nadège Loaëc

10-Iodo-11<i>H</i>-indolo[3,2-<i>c</i>]quinoline-6-carboxylic Acids Are Selective Inhibitors of DYRK1A

Hannes Falke, A. Chaikuad, Anja Becker et al. · Journal of Medicinal Chemistry · 2015 · 99 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells

Karima Bettayeb, Claire Delehouzé, Nadège Loaëc et al. · Genes & Cancer · 2010 · 86 citations · Full text

Medicine, Oncology, Pharmacology +15

Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A

Thu Lan Nguyen, Arnaud Duchon, Antigoni Manousopoulou et al. · Disease Models & Mechanisms · 2018 · 86 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

CDK/CK1 inhibitors roscovitine and CR8 downregulate amplified MYCN in neuroblastoma cells

Claire Delehouzé, Klaus Godl, Nadège Loaëc et al. · Oncogene · 2013 · 69 citations

Medicine, Cancer Biology, Oncology +11

TRPC6 channel translocation into phagosomal membrane augments phagosomal function

Vladimir Riazanski, Aida G. Gabdoulkhakova, Lin S. Boynton et al. · Proceedings of the National Academy of Sciences · 2015 · 69 citations · Full text

Life Sciences, Cell Biology, Immunology +17