Kathy A. Aldern

Esterification of cidofovir with alkoxyalkanols increases oral bioavailability and diminishes drug accumulation in kidney

Stephanie L. Ciesla, Julissa Trahan, William Wan et al. · Antiviral Research · 2003 · 176 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Alkoxyalkyl Esters of Cidofovir and Cyclic Cidofovir Exhibit Multiple-Log Enhancement of Antiviral Activity against Cytomegalovirus and Herpesvirus Replication In Vitro

James R. Beadle, Caroll B. Hartline, Kathy A. Aldern et al. · Antimicrobial Agents and Chemotherapy · 2002 · 171 citations · Full text

Medicine, Infectious Diseases, Pharmacology +17

Increased Antiviral Activity of 1-O-Hexadecyloxypropyl-[2-14C]cidofovir in MRC-5 Human Lung Fibroblasts Is Explained by Unique Cellular Uptake and Metabolism

Kathy A. Aldern, Stephanie L. Ciesla, Kristine L. Winegarden et al. · Molecular Pharmacology · 2003 · 137 citations

Medicine, Infectious Diseases, Pharmacology +13

Cidofovir and (<i>S</i>)-9-[3-Hydroxy-(2-Phosphonomethoxy)Propyl]Adenine Are Highly Effective Inhibitors of Vaccinia Virus DNA Polymerase When Incorporated into the Template Strand

Wendy C. Magee, Kathy A. Aldern, Karl Y. Hostetler et al. · Antimicrobial Agents and Chemotherapy · 2007 · 86 citations

Life Sciences, Biochemistry, Pharmacology +17

Evaluation of Hexadecyloxypropyl-9- <i>R</i> -[2-(Phosphonomethoxy)Propyl]- Adenine, CMX157, as a Potential Treatment for Human Immunodeficiency Virus Type 1 and Hepatitis B Virus Infections

George R. Painter, Merrick R. Almond, Lawrence C. Trost et al. · Antimicrobial Agents and Chemotherapy · 2007 · 73 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17