Lawrence C. Trost

The mitochondrial permeability transition in toxic, hypoxic and reperfusion injury

John J. Lemasters, Anna‐Liisa Nieminen, Ting Qian et al. · Molecular and Cellular Biochemistry · 1997 · 212 citations

First Pharmacokinetic and Safety Study in Humans of the Novel Lipid Antiviral Conjugate CMX001, a Broad-Spectrum Oral Drug Active against Double-Stranded DNA Viruses

Wendy Painter, Alice Robertson, Lawrence C. Trost et al. · Antimicrobial Agents and Chemotherapy · 2012 · 175 citations · Full text

Intraocular Pressure, Blood Chemistry, Neurovirology +14

Development of CMX001 for the Treatment of Poxvirus Infections

Randall Lanier, Lawrence C. Trost, Tim Tippin et al. · Viruses · 2010 · 159 citations · Full text

Phosphonic Acid, Pathogenesis, Viral Pathogenesis +11

The mitochondrial permeability transition: a new pathophysiological mechanism for Reye's syndrome and toxic liver injury.

Lawrence C. Trost, John J. Lemasters · Journal of Pharmacology and Experimental Therapeutics · 1996 · 133 citations

Efficacy of therapeutic intervention with an oral ether–lipid analogue of cidofovir (CMX001) in a lethal mousepox model

Scott Parker, Erin Touchette, Christina Oberle et al. · Antiviral Research · 2007 · 102 citations · Full text

Lethal Mousepox Model, Medicine, Immunology +8