George R. Painter

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

Timothy P. Sheahan, Amy Sims, Shuntai Zhou et al. · Science Translational Medicine · 2020 · 1.1K citations · Full text

SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801

Angela Wahl, Lisa E. Gralinski, Claire Johnson et al. · Nature · 2021 · 418 citations · Full text

Covid-19 Pandemic, Covid-19, Sars-cov-2 Infection

Human Safety, Tolerability, and Pharmacokinetics of Molnupiravir, a Novel Broad-Spectrum Oral Antiviral Agent with Activity against SARS-CoV-2

Wendy Painter, Wayne Holman, Jim Bush et al. · Antimicrobial Agents and Chemotherapy · 2021 · 391 citations · Full text

Adverse Events, Geometric Half-life, Pharmacology +13

Small-Molecule Antiviral β- <scp>d</scp> - <i>N</i> ⁴ -Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance

Maria L. Agostini, Andrea J. Pruijssers, James D. Chappell et al. · Journal of Virology · 2019 · 344 citations · Full text

Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia

Märt Toots, Jeong-Joong Yoon, Robert M. Cox et al. · Science Translational Medicine · 2019 · 332 citations · Full text