Wayne Holman

Human Safety, Tolerability, and Pharmacokinetics of Molnupiravir, a Novel Broad-Spectrum Oral Antiviral Agent with Activity against SARS-CoV-2

Wendy Painter, Wayne Holman, Jim Bush et al. · Antimicrobial Agents and Chemotherapy · 2021 · 391 citations · Full text

Adverse Events, Geometric Half-life, Pharmacology +13

A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus

William A. Fischer, Joseph J. Eron, Wayne Holman et al. · Science Translational Medicine · 2021 · 348 citations · Full text

Molnupiravir, an Oral Antiviral Treatment for COVID-19

William A. Fischer, Joseph J. Eron, Wayne Holman et al. · 2021 · 215 citations · Full text

Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study

Saye Khoo, Richard J. Fitzgerald, Sean Ewings et al. · Journal of Antimicrobial Chemotherapy · 2021 · 111 citations · Full text

Molnupiravir versus placebo in unvaccinated and vaccinated patients with early SARS-CoV-2 infection in the UK (AGILE CST-2): a randomised, placebo-controlled, double-blind, phase 2 trial

Saye Khoo, Richard J. Fitzgerald, Geoffrey Saunders et al. · The Lancet Infectious Diseases · 2022 · 76 citations · Full text

Vaccination, Covid-19 Pandemic, Vaccine Trial +8