Focco van den Akker - Concepedia

Author

Focco van den Akker

Also Known As

Akker, Focco van den, F. Akker, F. Van Den Akker, F. Van den Akker, F. van Den Akker, F. van den Akker, Filippo Ingoglia, Focco Van Den Akker, Focco van Den Akker, Focco van den Akker

178

Publications

4.6K

Citations

H-Index

Concepts

All Affiliations

Case Western Reserve University Louis Stokes Cleveland VA Medical Center University of Washington Southern Methodist University University School

About

Focco van den Akker is an author at Case Western Reserve University specializing in medicine, biochemistry, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	18	24	1.5K
2	Natural Sciences	12	14	398
3	Health Sciences	3	3	152
4	Engineering	2	2	133
5	Public Health	1	1	60

Focco van den Akker

Publications

4.1K

Citations

H-Index

Page 1

	Year	Citations
Crystal structure of cholera toxin B‐pentamer bound to receptor G<sub>M1</sub> pentasaccharide E.A. Merritt, Steve Sarfaty, Focco van den Akker, Protein Science	1994	570
Mutations in the Transmembrane Natriuretic Peptide Receptor NPR-B Impair Skeletal Growth and Cause Acromesomelic Dysplasia, Type Maroteaux Cynthia F. Bartels, Hülya Bükülmez, Pius S. Padayatti, The American Journal of Human Genetics SclerostinSignal TransductionMolecular PhysiologyBone Morphogenic ProteinGenetic Disorder	2004	363
NO and CO differentially activate soluble guanylyl cyclase via a heme pivot‐bend mechanism Xiaolei Ma, Nazish Sayed, Annie Beuve, The EMBO Journal	2007	230
Desensitization of soluble guanylyl cyclase, the NO receptor, by S-nitrosylation Nazish Sayed, Padmamalini Baskaran, Xiaolei Ma, Proceedings of the National Academy of Sciences Isolated AortaCellular PhysiologyOxidative StressInflammationMolecular Pharmacology	2007	215
Structure of the dimerized hormone-binding domain of a guanylyl- cyclase-coupled receptor Focco van den Akker, Xiaolun Zhang, Masaru Miyagi, Nature Molecular PhysiologySignal TransductionBiochemistryG Protein-coupled ReceptorDimerized Hormone-binding Domain	2000	169
Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β-Lactamase Inhibitors and β-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234 Krisztina M. Papp‐Wallace, Nhu Q. Nguyen, Michael R. Jacobs, Journal of Medicinal Chemistry	2018	145
Crystal Structure of KPC-2: Insights into Carbapenemase Activity in Class A β-Lactamases<sup>,</sup> Ke Wei, Christopher R. Bethel, Jodi M. Thomson, Biochemistry	2007	130
Targeting Multidrug-Resistant <i>Acinetobacter</i> spp.: Sulbactam and the Diazabicyclooctenone β-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent Melissa D. Barnes, Vijay Kumar, Christopher R. Bethel, mBio	2019	114
Structure of Cinaciguat (BAY 58–2667) Bound to Nostoc H-NOX Domain Reveals Insights into Heme-mimetic Activation of the Soluble Guanylyl Cyclase Padmamalini Baskaran, Xiaolei Ma, Pete Dunten, Journal of Biological Chemistry	2010	100
PAS-mediated Dimerization of Soluble Guanylyl Cyclase Revealed by Signal Transduction Histidine Kinase Domain Crystal Structure Xiaolei Ma, Nazish Sayed, Padmamalini Baskaran, Journal of Biological Chemistry	2007	92

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