Concepedia

Tamara H. den Bleker

TH

Statistics

Publications

6

Citations

1.2K

H-Index

6

Active since

2007

Affiliations

Sanquin(Current)

University of Amsterdam

Genmab (Netherlands)

University Medical Center Utrecht

Utrecht University

Tamara H. den Bleker is an author at Sanquin specializing in life sciences, biochemistry, and immunology.

Publications per year

2007–2012

6

Publications

6

Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

Marijn van der Neut Kolfschoten, Janine Schuurman, Mario Losen et al. · Science · 2007 · 975 citations

, , +17

Species-Specific Determinants in the IgG CH3 Domain Enable Fab-Arm Exchange by Affecting the Noncovalent CH3–CH3 Interaction Strength

Aran F. Labrijn, Theo Rispens, Joyce Meesters et al. · The Journal of Immunology · 2011 · 131 citations · Full text

, , +9

Fc–Fc interactions of human IgG4 require dissociation of heavy chains and are formed predominantly by the intra-chain hinge isomer

Theo Rispens, Joyce Meesters, Tamara H. den Bleker et al. · Molecular Immunology · 2012 · 48 citations

, , +11

Crystal structure of the human IgG4 CH3 dimer reveals the role of Arg409 in the mechanism of Fab-arm exchange

Anna M. Davies, Theo Rispens, Tamara H. den Bleker et al. · Molecular Immunology · 2012 · 42 citations

, , +7

Hybrid IgG4/IgG4 Fc antibodies form upon ‘Fab-arm’ exchange as demonstrated by SDS-PAGE or size-exclusion chromatography

Theo Rispens, Tamara H. den Bleker, Rob C. Aalberse · Molecular Immunology · 2010 · 27 citations

, , +14

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