The MEK/MAPK pathway is involved in the resistance of breast cancer cells to the EGFR tyrosine kinase inhibitor gefitinib

Nicola Normanno, Antonella De Luca, Monica R. Maiello, +6

Journal of Cellular Physiology

Tumor-Associated Fibroblasts Promote HER2-Targeted Therapy Resistance through FGFR2 Activation

Patricia Fernández‐Nogueira, Mario Mancino, Gemma Fuster, +19

Clinical Cancer Research

Substance P Autocrine Signaling Contributes to Persistent HER2 Activation That Drives Malignant Progression and Drug Resistance in Breast Cancer

Susana García‐Recio, Gemma Fuster, Patricia Fernández‐Nogueira, +12

Cancer Research

Identification of Cripto-1 as a Novel Serologic Marker for Breast and Colon Cancer

Caterina Bianco, Luigi Strizzi, Mario Mancino, +13

Clinical Cancer Research

Cripto-1 Is Required for Hypoxia to Induce Cardiac Differentiation of Mouse Embryonic Stem Cells

Caterina Bianco, Catherine J. Cotten, Enza Lonardo, +10

American Journal Of Pathology

Induced Pluripotent Stem CellDevelopmental BiologyMedicineStem Cell ResearchMorphogenesis +5

Growth Factor Induction of Cripto-1 Shedding by Glycosylphosphatidylinositol-Phospholipase D and Enhancement of Endothelial Cell Migration

Kazuhide Watanabe, Caterina Bianco, Luigi Strizzi, +10

Journal of Biological Chemistry

ImmunologyCell GrowthCellular PhysiologyTumor BiologyInflammation +20

Requirement of Glycosylphosphatidylinositol Anchor of Cripto-1 for trans Activity as a Nodal Co-receptor

Kazuhide Watanabe, Shin Hamada, Caterina Bianco, +6

Journal of Biological Chemistry

Molecular RegulationParacrine ActivityTrans ActivityCellular PhysiologySignaling Pathway +16

Differential expression of neurogenes among breast cancer subtypes identifies high risk patients

Patricia Fernández‐Nogueira, Paloma Bragado, Vanessa Almendro, +5

Oncotarget

Histamine receptor 1 inhibition enhances antitumor therapeutic responses through extracellular signal-regulated kinase (ERK) activation in breast cancer

Patricia Fernández‐Nogueira, Aleix Noguera‐Castells, Gemma Fuster, +10

Cancer Letters

Breast OncologyEndocrine-related CancerMedicineTumor GrowthReceptor Tyrosine Kinase +13

Breast cancer cells with acquired resistance to the EGFR tyrosine kinase inhibitor gefitinib show persistent activation of MAPK signaling

Nicola Normanno, Manuela Campiglio, Monica R. Maiello, +5

Breast Cancer Research and Treatment

Breast OncologySignaling PathwayMedicineReceptor Tyrosine KinaseBreast Cancer Cells +6