eIF4E – from translation to transformation

Yaël Mamane, Emmanuel Petroulakis, Liwei Rong, +3

Oncogene

Eif4e –Translational BiologyTranslational ResearchTranslational AdvanceData Transformation (Computing)

Structural and Functional Analysis of Interferon Regulatory Factor 3: Localization of the Transactivation and Autoinhibitory Domains

Rongtuan Lin, Yaël Mamane, John Hiscott

Molecular and Cellular Biology

Viral ReplicationAmino AcidsImmunologyAutoinhibitory DomainsGene Regulatory Network +14

Selective DNA Binding and Association with the CREB Binding Protein Coactivator Contribute to Differential Activation of Alpha/Beta Interferon Genes by Interferon Regulatory Factors 3 and 7

Rongtuan Lin, Pierre Génin, Yaël Mamane, +1

Molecular and Cellular Biology

Molecular RegulationAlpha/beta Interferon GenesGeneticsMolecular BiologyGene Regulatory Network +15

Multiple Regulatory Domains Control IRF-7 Activity in Response to Virus Infection

Rongtuan Lin, Yaël Mamane, John Hiscott

Journal of Biological Chemistry

mTOR signaling: implications for cancer and anticancer therapy

Emmanuel Petroulakis, Yaël Mamane, Olivier Le Bacquer, +2

British Journal of Cancer

Epigenetic Activation of a Subset of mRNAs by eIF4E Explains Its Effects on Cell Proliferation

Yaël Mamane, Emmanuel Petroulakis, Yvan Martineau, +4

PLoS ONE

HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators

Rongtuan Lin, Pierre Génin, Yaël Mamane, +5

Oncogene

Molecular VirologyCbp/p300 CoactivatorsVirf-1 RepressesPathogenesisImmunology +6

CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition

David Gallo, Jordan T.F. Young, Jimmy Fourtounis, +33

Nature

The C3a Anaphylatoxin Receptor Is a Key Mediator of Insulin Resistance and Functions by Modulating Adipose Tissue Macrophage Infiltration and Activation

Yaël Mamane, Chi Chung Chan, Geneviève Lavallée, +9

Diabetes

p53-Dependent Translational Control of Senescence and Transformation via 4E-BPs

Emmanuel Petroulakis, Armen Parsyan, Ryan J.O. Dowling, +15

Cancer Cell

Cell RegulationMolecular BiologyCellular SenescenceCell BiologyP53-dependent Translational Control