John Hiscott

Triggering the Interferon Antiviral Response Through an IKK-Related Pathway

Sonia Sharma, Benjamin R. tenOever, Nathalie Grandvaux et al. · Science · 2003 · 1.7K citations

Ikappab Kinase, Signal Transduction, Rapid Induction +14

Virus-Dependent Phosphorylation of the IRF-3 Transcription Factor Regulates Nuclear Translocation, Transactivation Potential, and Proteasome-Mediated Degradation

Rongtuan Lin, Christophe Heylbroeck, Paula M. Pitha et al. · Molecular and Cellular Biology · 1998 · 913 citations · Full text

VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents

David F. Stojdl, Brian D. Lichty, Benjamin R. tenOever et al. · Cancer Cell · 2003 · 841 citations · Full text

Pathogenesis, Immunology, Innate Immune System +7

Characterization of a functional NF-kappa B site in the human interleukin 1 beta promoter: evidence for a positive autoregulatory loop.

John Hiscott, James J. Marois, Jenny Garoufalis et al. · Molecular and Cellular Biology · 1993 · 592 citations · Full text

Immune Regulation, Immunology, Immunologic Mechanism +21

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

Ashutosh Kumar, Jaharul Haque, Judith Lacoste et al. · Proceedings of the National Academy of Sciences · 1994 · 562 citations · Full text

Engineering, Molecular Regulation, Immunology +18