Valentina Manzini

The folate antagonist methotrexate diminishes replication of the coronavirus SARS-CoV-2 and enhances the antiviral efficacy of remdesivir in cell culture models

Kim M. Stegmann, Antje Dickmanns, Sabrina Gerber et al. · Virus Research · 2021 · 49 citations · Full text

Cell Culture Models, Immunology, Antiviral Drug Development +7

MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression

Celeste Giansanti, Valentina Manzini, Antje Dickmanns et al. · Cell Reports · 2022 · 27 citations · Full text

Chromatin, Genome Instability, Functional P53 +12

Mdm4 supports DNA replication in a p53-independent fashion

Kai Wohlberedt, Ina Klusmann, Polina K. Derevyanko et al. · Oncogene · 2020 · 23 citations · Full text

Molecular Biology, Natural Sciences, Genome Instability +1

MDM2-Driven Ubiquitination Rapidly Removes p53 from Its Cognate Promoters

Kester Mo Henningsen, Valentina Manzini, Anna Magerhans et al. · Biomolecules · 2021 · 21 citations · Full text

The integrated stress response induces R-loops and hinders replication fork progression

Josephine Ann Mun Yee Choo, Denise Schlösser, Valentina Manzini et al. · Cell Death and Disease · 2020 · 13 citations · Full text