Nathan Morgan

Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

Wei Meng, Bruce A. Ellsworth, Alexandra A. Nirschl et al. · Journal of Medicinal Chemistry · 2008 · 612 citations · Full text

Metabolic Syndrome, Diabetes Management, Biochemistry +10

PHYSIOLOGIC AND MOLECULAR CHARACTERIZATION OF THE ROLE OF NITRIC OXIDE IN HEMORRHAGIC SHOCK

Edward Kelly, Nishit S. Shah, Nathan Morgan et al. · Shock · 1997 · 62 citations

Nitric Oxide, Immunology, Redox Biology +18

Aglycone exploration of C-arylglucoside inhibitors of renal sodium-dependent glucose transporter SGLT2

Bruce A. Ellsworth, Wei Meng, Manorama M. Patel et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 57 citations · Full text

C-arylglucoside Inhibitors, Renal Function, Biochemistry +10

Optimization of Activity, Selectivity, and Liability Profiles in 5-Oxopyrrolopyridine DPP4 Inhibitors Leading to Clinical Candidate (<i>Sa</i>)-2-(3-(Aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5<i>H</i>-pyrrolo[3,4-<i>b</i>]pyridin-6(7<i>H</i>)-yl)-<i>N</i>,<i>N</i>-dimethylacetamide (BMS-767778)

Pratik Devasthale, Ying Wang, Wei Wang et al. · Journal of Medicinal Chemistry · 2013 · 44 citations · Full text

Combinatorial Chemistry, Pharmaceutical Science, Organic Chemistry +23

Exploring Cuneanes as Potential Benzene Isosteres and Energetic Materials: Scope and Mechanistic Investigations into Regioselective Rearrangements from Cubanes

Jeong‐Yu Son, Santeri Aikonen, Nathan Morgan et al. · Journal of the American Chemical Society · 2023 · 38 citations · Full text