Angela Wolford

Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1<i>H</i>-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy

Kimberly O. Cameron, Daniel W. Kung, Amit S. Kalgutkar et al. · Journal of Medicinal Chemistry · 2016 · 115 citations · Full text

Renal Inflammation, Pharmacotherapy, Insulin Signaling +19

A Novel Relay Method for Determining Low-Clearance Values

Li Di, Patrick Trapa, R. Scott Obach et al. · Drug Metabolism and Disposition · 2012 · 108 citations

A “middle-out” approach to human pharmacokinetic predictions for OATP substrates using physiologically-based pharmacokinetic modeling

Rui Li, Hugh A. Barton, Phillip D. Yates et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2014 · 77 citations

Pharmacokinetic Modeling, Medicine, Physiology +6

Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)

Kim Huard, Janice A. Brown, Jessica Jones et al. · Scientific Reports · 2015 · 68 citations · Full text

Medicinal Chemistry, Biochemistry, Citrate Transport +13

Utility of the carboxylesterase inhibitor<i>bis</i>-<i>para</i>-nitrophenylphosphate (BNPP) in the plasma unbound fraction determination for a hydrolytically unstable amide derivative and agonist of the TGR5 receptor

Heather Eng, Mark Niosi, Thomas S. McDonald et al. · Xenobiotica · 2010 · 61 citations