Michael C. M. Kwok

USP7 small-molecule inhibitors interfere with ubiquitin binding

Lorna Kategaya, Paola Di Lello, Lionel Rougé et al. · Nature · 2017 · 332 citations · Full text

Molecular Docking, Ubiquitin Binding, Drug Target +7

Localization, Purification, and Functional Reconstitution of the P4-ATPase Atp8a2, a Phosphatidylserine Flippase in Photoreceptor Disc Membranes

Jonathan A. Coleman, Michael C. M. Kwok, Robert S. Molday · Journal of Biological Chemistry · 2009 · 185 citations · Full text

Proteinlipid Interaction, Molecular Biology, P-type Atpases +18

Proteomics of Photoreceptor Outer Segments Identifies a Subset of SNARE and Rab Proteins Implicated in Membrane Vesicle Trafficking and Fusion

Michael C. M. Kwok, Juha M. Holopainen, Laurie L. Molday et al. · Molecular & Cellular Proteomics · 2008 · 122 citations · Full text

Protein Secretion, Molecular Biology, Cellular Physiology +19

Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer’s disease

Gai Ayalon, Seung-Hye Lee, Oskar Adolfsson et al. · Science Translational Medicine · 2021 · 106 citations · Full text

Immunology, Neurochemical Biomarkers, Transgenic Mouse Model +21

Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation

Lionel Rougé, Travis W. Bainbridge, Michael C. M. Kwok et al. · Structure · 2016 · 102 citations · Full text

Usp7 Substrate Recognition, Protein Function, Biochemistry +5