Leonardo da Silva Lara

Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound

Leonardo da Silva Lara, Caroline dos Santos Moreira, Cláudia M. Calvet et al. · European Journal of Medicinal Chemistry · 2017 · 48 citations

Promising Hit Compound, Antiparasitic Agent, Medicine +6

Synthesis, structure-activity relationship and trypanocidal activity of pyrazole-imidazoline and new pyrazole-tetrahydropyrimidine hybrids as promising chemotherapeutic agents for Chagas disease

M. Monteiro, Guilherme C. Lechuga, Leonardo da Silva Lara et al. · European Journal of Medicinal Chemistry · 2019 · 35 citations · Full text

Trypanocidal Activity, Biochemistry, Antiparasitic Agent +10

<i>N</i>-Nitrosulfonamides as Carbonic Anhydrase Inhibitors: A Promising Chemotype for Targeting Chagas Disease and Leishmaniasis

Alessandro Bonardi, Alane Beatriz Vermelho, Verônica da Silva Cardoso et al. · ACS Medicinal Chemistry Letters · 2018 · 32 citations · Full text

Trypanosoma cruzi infection of human induced pluripotent stem cell-derived cardiomyocytes: an in vitro model for drug screening for Chagas disease

Leonardo da Silva Lara, Leonardo Carmo de Andrade-Lima, Cláudia M. Calvet et al. · Microbes and Infection · 2018 · 26 citations

Translational Medicine, Chagas Disease, Parasitic Protozoa +7

Structural Optimization and Biological Activity of Pyrazole Derivatives: Virtual Computational Analysis, Recovery Assay and 3D Culture Model as Potential Predictive Tools of Effectiveness against Trypanosoma cruzi

Lorraine Martins Rocha Orlando, Guilherme C. Lechuga, Leonardo da Silva Lara et al. · Molecules · 2021 · 18 citations · Full text