Frederick Hecht

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

Jason M. Brenchley, David A. Price, Timothy W. Schacker et al. · Nature Medicine · 2006 · 3.5K citations

Life Sciences, Immunology, Infectious Diseases +17

Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population

David R. Bangsberg, Frederick Hecht, Edwin D. Charlebois et al. · AIDS · 2000 · 1K citations

Public Health, Infectious Diseases, Hiv Control +16

Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load

Steven G. Deeks, Christina M. Ramirez, Hua Guo et al. · Blood · 2004 · 788 citations

Life Sciences, Immunology, Infectious Diseases +17

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

R. Brad Jones, Lishomwa C. Ndhlovu, Jason D. Barbour et al. · The Journal of Experimental Medicine · 2008 · 748 citations · Full text

Life Sciences, Immunology, Infectious Diseases +14

HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality

Sergio Serrano‐Villar, Talía Sainz, Sulggi A. Lee et al. · PLoS Pathogens · 2014 · 614 citations · Full text

Life Sciences, Immunology, Infectious Diseases +16