Concepedia

Guanglei Zhai

GZ

4

Publications

120

Citations

4

H-Index

2020

Active since

Affiliations

Shanghai Institute of Materia Medica(Current)

Shanghai University of Traditional Chinese Medicine

Roche (Switzerland)

Roche (China)

Chinese Academy of Sciences

Guanglei Zhai is an author at Shanghai Institute of Materia Medica specializing in drug discovery, medicine, and pharmacology.

Top concepts

Publications per year

2020–2024

4

Publications

4

Discovery of Pyrido[2,3-<i>b</i>]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV

Yimin Hu, Houguang Shi, Mingwei Zhou et al. · Journal of Medicinal Chemistry · 2020 · 65 citations

Structural basis for dimerization of a paramyxovirus polymerase complex

Jin Xie, Mohamed Ouizougun-Oubari, Li Wang et al. · Nature Communications · 2024 · 30 citations · Full text

Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay

Yusen Xiang, Guanglei Zhai, Yaozong Li et al. · International Journal of Biological Macromolecules · 2022 · 13 citations · Full text

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Discovery and mechanism of action of Thonzonium bromide from an FDA-approved drug library with potent and broad-spectrum inhibitory activity against main proteases of human coronaviruses

Ruyu Wang, Guanglei Zhai, Guanghao Zhu et al. · Bioorganic Chemistry · 2022 · 12 citations · Full text

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