Ruyu Wang

Identification of Vitamin K3 and its analogues as covalent inhibitors of SARS-CoV-2 3CLpro

Ruyu Wang, Qing Hu, Haonan Wang et al. · International Journal of Biological Macromolecules · 2021 · 40 citations · Full text

Vitamin K Antagonists, Covalent Inhibitors, Biochemistry +10

Danshensu inhibits SARS-CoV-2 by targeting its main protease as a specific covalent inhibitor and discovery of bifunctional compounds eliciting antiviral and anti-inflammatory activity

Ruyu Wang, Xuwen Chen, Hongtao Li et al. · International Journal of Biological Macromolecules · 2023 · 20 citations

Protease Inhibitors, Medicine, Immunology +10

Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay

Yusen Xiang, Guanglei Zhai, Yaozong Li et al. · International Journal of Biological Macromolecules · 2022 · 13 citations · Full text

Inflammation, Medicine, Ginkgolic Acids +6

Discovery and mechanism of action of Thonzonium bromide from an FDA-approved drug library with potent and broad-spectrum inhibitory activity against main proteases of human coronaviruses

Ruyu Wang, Guanglei Zhai, Guanghao Zhu et al. · Bioorganic Chemistry · 2022 · 12 citations · Full text

Biochemistry, Medicine, Thonzonium Bromide +8