Concepedia

Houguang Shi

HS

Statistics

Publications

5

Citations

188

H-Index

5

Active since

2017

Affiliations

Roche (China)(Current)

Roche (Switzerland)

Houguang Shi is an author at Roche (China) specializing in drug discovery, medicinal chemistry, and pharmacology.

Publications per year

2017–2023

5

Publications

5

Discovery of Pyrido[2,3-<i>b</i>]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV

Yimin Hu, Houguang Shi, Mingwei Zhou et al. · Journal of Medicinal Chemistry · 2020 · 71 citations

, , +17

Discovery and Pre-Clinical Characterization of Third-Generation 4-H Heteroaryldihydropyrimidine (HAP) Analogues as Hepatitis B Virus (HBV) Capsid Inhibitors

Zongxing Qiu, Xianfeng Lin, Weixing Zhang et al. · Journal of Medicinal Chemistry · 2017 · 59 citations · Full text

, , +16

Discovery of Linvencorvir (RG7907), a Hepatitis B Virus Core Protein Allosteric Modulator, for the Treatment of Chronic HBV Infection

Weixing Zhang, Lei Guo, Haixia Liu et al. · Journal of Medicinal Chemistry · 2023 · 33 citations · Full text

, , +17

A New Approach of Mitigating CYP3A4 Induction Led to the Discovery of Potent Hepatitis B Virus (HBV) Capsid Inhibitor with Optimal ADMET Profiles

Xianfeng Lin, Houguang Shi, Weixing Zhang et al. · Journal of Medicinal Chemistry · 2019 · 15 citations · Full text

, , +15

From α-keto acids to nitrile oxides enabled by copper nitrate: a facile access to fused isoxazolines

Tianqi Liu, Bingxin Liu, Houguang Shi et al. · Organic Chemistry Frontiers · 2021 · 10 citations

, , +11

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