Zelpha D’Souza

A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency

Julie Tordo, Claire O’Leary, André Saraiva Leão Marcelo Antunes et al. · Brain · 2018 · 127 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15

Brain‐targeted stem cell gene therapy corrects mucopolysaccharidosis type II via multiple mechanisms

Hélène F.E. Gleitz, Ai Yin Liao, James Cook et al. · EMBO Molecular Medicine · 2018 · 87 citations · Full text

Medicine, Neurology, Neuroscience +17

Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy

Rebecca Holley, Stuart Ellison, Daniel Fil et al. · Brain · 2017 · 79 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Kcnn4 Is a Regulator of Macrophage Multinucleation in Bone Homeostasis and Inflammatory Disease

Heeseog Kang, Audrey Kerloc’h, Maxime Rotival et al. · Cell Reports · 2014 · 65 citations · Full text

Life Sciences, Genetics, Immunology +17

Combined ChIP-Seq and transcriptome analysis identifies AP-1/JunD as a primary regulator of oxidative stress and IL-1β synthesis in macrophages

Richard Hull, Prashant K. Srivastava, Zelpha D’Souza et al. · BMC Genomics · 2013 · 50 citations · Full text

Life Sciences, Immunology, Pathobiology +17