Ashutosh Dhingra

Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression

Peter Reinhardt, Benjamin Schmid, Lena F. Burbulla et al. · Cell stem cell · 2013 · 511 citations · Full text

Life Sciences, Genetics, Neuroscience +15

A Pentanucleotide ATTTC Repeat Insertion in the Non-coding Region of DAB1, Mapping to SCA37, Causes Spinocerebellar Ataxia

Ana I. Seixas, Joana R. Loureiro, Cristina Costa et al. · The American Journal of Human Genetics · 2017 · 152 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

C9orf72 is differentially expressed in the central nervous system and myeloid cells and consistently reduced in C9orf72, MAPT and GRN mutation carriers

Patrizia Rizzu, Cornelis Blauwendraat, Sasja Heetveld et al. · Acta Neuropathologica Communications · 2016 · 81 citations · Full text

Life Sciences, Genetics, Neuroscience +17

In Vitro Differentiated Human Stem Cell-Derived Neurons Reproduce Synaptic Synchronicity Arising during Neurodevelopment

Filip Rosa, Ashutosh Dhingra, Betül Seher Uysal et al. · Stem Cell Reports · 2020 · 44 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 ALS/FTD

Mareike Czuppa, Ashutosh Dhingra, Qihui Zhou et al. · Cell Reports · 2022 · 31 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17