Takahiro Hotta

Discovery of JTZ-951: A HIF Prolyl Hydroxylase Inhibitor for the Treatment of Renal Anemia

Yosuke Ogoshi, Takuya Matsui, Ikuo MITANI et al. · ACS Medicinal Chemistry Letters · 2017 · 52 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery of (1<i>S</i>,2<i>R</i>,3<i>R</i>)-2,3-Dimethyl-2-phenyl-1-sulfamidocyclopropanecarboxylates: Novel and Highly Selective Aggrecanase Inhibitors

Makoto Shiozaki, Katsuya Maeda, Tomoya Miura et al. · Journal of Medicinal Chemistry · 2011 · 51 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Discovery of potent liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitors, thiazole-4-acetic acid derivatives, for the treatment of diabetes, hepatic steatosis, and obesity

Minoru Ubukata, Ikuo MITANI, Yuichi Nakagawa et al. · European Journal of Medicinal Chemistry · 2018 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Separation of an inhibitor of erythropoiesis in "middle molecules" from hemodialysate from patients with chronic renal failure.

Atsushi Saito, I Suzuki, Tai Gi Chung et al. · Clinical Chemistry · 1986 · 28 citations · Full text

Medicine, Biochemistry, Hematology +13