Makoto Shiozaki

Nitric Oxide Donor SNAP Induces Apoptosis in Smooth Muscle Cells through cGMP-Independent Mechanism

Eisuke Nishio, Kouji Fukushima, Makoto Shiozaki et al. · Biochemical and Biophysical Research Communications · 1996 · 100 citations

Molecular Physiology, Reactive Nitrogen Specie, Cgmp-independent Mechanism +12

Pharmacological properties of JTE-052: a novel potent JAK inhibitor that suppresses various inflammatory responses in vitro and in vivo

Atsuo Tanimoto, Yoshihiro Ogawa, Chika Oki et al. · Inflammation Research · 2014 · 99 citations · Full text

SAR Exploration Guided by LE and Fsp ³ : Discovery of a Selective and Orally Efficacious RORγ Inhibitor

Kazuyuki Hirata, Masayuki Kotoku, Noriyoshi Seki et al. · ACS Medicinal Chemistry Letters · 2015 · 58 citations · Full text

Discovery of a Janus Kinase Inhibitor Bearing a Highly Three-Dimensional Spiro Scaffold: JTE-052 (Delgocitinib) as a New Dermatological Agent to Treat Inflammatory Skin Disorders

Satoru Noji, Yoshinori Hara, Tomoya Miura et al. · Journal of Medicinal Chemistry · 2020 · 52 citations · Full text

Discovery of (1<i>S</i>,2<i>R</i>,3<i>R</i>)-2,3-Dimethyl-2-phenyl-1-sulfamidocyclopropanecarboxylates: Novel and Highly Selective Aggrecanase Inhibitors

Makoto Shiozaki, Katsuya Maeda, Tomoya Miura et al. · Journal of Medicinal Chemistry · 2011 · 49 citations · Full text

Aggrecanase Inhibitors, Medicinal Chemistry, Anti-inflammatory +12